Why our Clients Choose Us?

We help our clients accelerate and improve their drug development efforts by improving:

  • MOA elucidation

  • Patient stratification

  • Measurement of treatment response

  • Support of antifibrotic claims

  • Holistic evaluation of therapeutic effects

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Our Products and Services

FibroMAP

Single-Fiber Spatial Histology for Phenotypic Mapping of Fibrosis and Fibrotypes discovery

FibroNest

Quantitative Digital Pathology Platform for Fibrosis Assessment and Biomarker Discovery

FibroNest™ is PharmaNest’s quantitative digital pathology platform for fibrosis analysis.
It extracts hundreds of single-fiber and tissue-level parameters from histology slides to measure fibrosis, inflammation, and tissue remodeling with precision.
Using AI-assisted image segmentation and feature extraction, it quantifies collagen organization, density, and texture across tissue compartments.


FibroNest provides continuous, reproducible biomarkers aligned with histological staging and clinical outcomes. It is used across preclinical and clinical studies to evaluate disease progression and therapeutic efficacy from conventional Digital Pathology images.

FibroMAP™ is PharmaNest’s single-fiber spatial histology platform.
It clusters millions of collagen fibers from digital pathology images using UMAP, grouping them into phenotypic “fibrotypes” that capture tissue-level remodeling patterns. Each fibrotype represents a reproducible micro-architectural signature linked to disease stage or therapeutic response.
The method goes beyond bulk collagen quantification, integrating geometry, orientation, and topology of individual fibers.


FibroMAP enables visualization, stratification, and comparison of fibrotic phenotypes across tissues, treatments, and disease models.

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About PharmaNest

PharmaNest is a digital pathology and AI company specializing in the quantitative analysis of fibrosis and tissue remodeling across preclinical and clinical research. Our proprietary FibroNest™ and FibroMAP™ platforms transform histological slides into rich, multidimensional datasets, enabling precise measurement of collagen architecture, inflammation, and tissue repair at the single-fiber level.

By integrating advanced image analytics, spatial phenotyping, and machine learning, PharmaNest provides reproducible, quantitative biomarkers that bridge preclinical models and human trials. Our technologies are trusted by leading pharmaceutical and academic partners worldwide to accelerate drug development in MASH, IBD, Crohn’s disease, PSC, EoE, cardiac, and pulmonary fibrosis.

Through scientific rigor, innovation, and collaboration, PharmaNest is redefining how fibrosis is quantified—bringing clarity, precision, and translational value to the study of tissue remodeling and disease progression.

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